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Blueberries vs Breast Cancer

From a NIH study published online April 13, 2010
---> Abstract
"Dietary phytochemicals are known to exhibit a variety of anti-carcinogenic properties. This study investigated the chemopreventive activity of blueberry extract in triple negative breast cancer cell lines in vitro and in vivo."
"Blueberry decreased cell proliferation in HCC38, HCC1937 and MDA-MB-231 cells with no effect on the non-tumorigenic MCF-10A cell line."

 "The aims of this study were to determine the antitumor activity of a whole blueberry preparation against MDA-MB-231 cells.  Preliminary results showed that among a panel of whole food preparations, blueberry exhibited the highest antiproliferative effect against MDA-MB-231 cells."

"One aim in developing chemopreventive agents is to identify those that are easily accessible and nontoxic; therefore, blueberry was chosen for further study."

A large number of natural products, including berries, have been shown to inhibit metastatic potential in cancer cell lines, including prostate, lung, breast, and fibrosarcoma.

---> "The results of our studies suggest that the oral intake of blueberries could be a key component of long-term breast cancer prevention strategies. We showed that blueberry ingestion in mice decreased not only tumor growth but also the activity of markers for metastatic potential in breast tumors."

"The dose of blueberry in our study is equal to a fresh blueberry intake equal to 4.3 oz of fresh blueberries per day for a 130-lb person. A single serving of fresh blueberries is 6 oz, which is an attainable intake for the average person."

Source NIH:
"Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells"

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