"vitamin C is effective in melanoma and a large panel of tumor cell lines"Neuroblastoma (NB) is the most common solid extracranial tumor of childhood; many patients have highly aggressive disease that is ultimately fatal. Therefore, less toxic and more effective therapy must be found."
Conclusion of this research study:
"This study demonstrates that sodium ascorbate, Vitamin C, is highly toxic to neuroblastoma cell lines.
We could observe dose- and time-dependent induction of apoptosis in all NB cell lines.
This work, together with others, supports the use of vitamin C as an anticancer agent; in particular we suggest exploring the use of high dose intravenous ascorbate in controlled studies. Vitamin C is relatively tumor specific, non toxic and inexpensive, in contrast to many chemotherapeutic agents in use."
Sodium Ascorbate (Vitamin C) Induces Apoptosis in Neuroblastoma
* NOTE: emphasis is authors
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